Shanghai Chemtron Biotech Co.Ltd.

Urinary Microalbumin and Hypertension

Recent clinical studies have carried out large-scale clinical observation on the correlation between hypertension and increased MUA, indicating that MUA is an indicator of renal damage in hypertension. Some studies have found that MUA is significantly increased in patients with essential hypertension, which is mainly related to systolic blood pressure and is an independent risk factor for stroke. Studies on patients with essential hypertension show that the incidence of cardiac hypertrophy, ventricular septum thickening and arrhythmia in MUA positive patients is higher than that in MUA negative patients, and there are significant statistical differences between the two. Experimental studies have shown that the increase of MUA is related to the increase of angiotensin II (AII). The use of AII inhibitor can improve the function of renin-angiotensin II and reduce the MUA level. Other studies have shown that the use of b receptor blockers can also improve glomerular filtration function and reduce MUA excretion. Currently, it is believed that the treatment of MUA positive people must be strengthened, and their blood pressure is best controlled below 130/80mmhg.

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